Sr. Clinical Trial Manager

June 3, 2026

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At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio: <a href="https://careers.bms.com/rayzebio/" target="_blank" rel="noopener noreferrer">https://careers.bms.com/rayzebio/</a><div><div>Summary </div><div>The Sr. Clinical Trial Manager/Clinical Trial Manager, Clinical Operations is responsible for the oversight, planning and delivery of assigned clinical study(ies) within the RayzeBio programs, including oversight and management of the study Clinical Research Organization (CRO) and Vendors according to and in compliance with corporate and program Standard Operating Procedures (SOPs), Good Clinical Practice (GCP)/International Conference on Harmonization (ICH) guidelines and other applicable federal (FDA) and state regulations, in order to achieve established study goals within timelines and budget and of the highest quality. </div><div>Job Responsibilities </div><div>Essential duties and responsibilities include the following. Other duties may be assigned. </div><div><ul><li>Lead the planning, execution, and closeout of clinical trials from Phase I–III </li></ul></div><div><ul><li>Oversees and manages CROs and vendors to ensure that the study(ies) are completed on time, within budget, and in compliance with RayzeBio SOPs, FDA regulations and ICH/GCP guidelines </li></ul></div><div><ul><li>Leads the cross-functional study execution team in achieving the study goals and deliverables </li></ul></div><div><ul><li>Plan and execute study timelines </li></ul></div><div><ul><li>Monitor study progress, including enrollment, site performance, data quality, and key risk indicators and proactively escalates issues to key internal stakeholders to ensure timely resolution of issues </li></ul></div><div><ul><li>Identify, assess, and mitigate operational risks; escalate issues as needed </li></ul></div><div><ul><li>Manage study CRO and vendor budgets and invoicing procedures according to study contract </li></ul></div><div><ul><li>Lead/support country and site feasibility, selection, and activation strategies </li></ul></div><div><ul><li>Active participant in CRO and vendor meetings, responsible to review key CRO and vendor study operational plans and provides input to operational strategy, including country and site feasibility and start-up </li></ul></div><div><ul><li>Summarizes CRO, vendor and site performance data and escalates study risks to the Clinical Operations Program Lead / Head of Clinical Operations </li></ul></div><div><ul><li>Performs other related duties as assigned </li></ul></div></div><div><div><ul><li>Up to 20% travel required </li></ul></div><div> </div><div>Education and Experience </div><div><ul><li>Minimum 5-7 years clinical operations experience within biotech, pharma or CRO industry </li></ul></div><div><ul><li>BA/BS degree, scientific or healthcare discipline preferred </li></ul></div><div> </div><div>Skills and Qualifications </div><div><ul><li>Independent professional who proactively communicates frequently and effectively. </li></ul></div><div><ul><li>Detail and action-oriented, organized and committed to quality and consistency. </li></ul></div><div><ul><li>Ability to work successfully in cross-functional teams. </li></ul></div><div><ul><li>Ability to work in a dynamic environment with a high degree of flexibility. </li></ul></div><div><ul><li>Expertise in Microsoft Project and Smartsheets desired. </li></ul></div><div> </div><div>Work Environment </div><div>The noise level in the work environment is usually moderate. </div></div>If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.<div><div><div><div><div><div><div><div><div><div><div><div><div><div>Compensation Overview:</div></div></div></div></div></div></div></div></div></div></div></div></div></div>Remote - United States - US: $149,860 - $181,595 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank" rel="noopener noreferrer"> https://careers.bms.com/life-at-bms/.</a> Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:<ul><li>Health Coverage: Medical, pharmacy, dental, and vision care.</li><li>Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).</li><li>Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.</li></ul>Work-life benefits include:Paid Time Off<ul><li>US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)</li><li>Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays</li></ul>Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.RayzeBio and Bristol Myers SquibbRayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization.Supporting People with DisabilitiesBMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank" rel="noopener noreferrer">adastaffingsupport@bms.com</a>. Visit <a href="https://careers.bms.com/eeo-accessibility" target="_blank" rel="noopener noreferrer">careers.bms.com/</a><a href="https://careers.bms.com/eeo-accessibility" target="_blank" rel="noopener noreferrer">eeo</a><a href="https://careers.bms.com/eeo-accessibility" target="_blank" rel="noopener noreferrer">-accessibility</a> to access our complete Equal Employment Opportunity statement.Candidate RightsBMS and RayzeBio will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: <a href="https://careers.bms.com/california-residents/" target="_blank" rel="noopener noreferrer">https://careers.bms.com/california-residents/</a>Data ProtectionWe will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at <a href="https://careers.bms.com/fraud-protection/" target="_blank" rel="noopener noreferrer">https://careers.bms.com/fraud-protection/</a>Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at <a href="mailto:TAEnablement@bms.com" target="_blank" rel="noopener noreferrer">TAEnablement@bms.com</a>. Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response.R1602881 : Sr. Clinical Trial Manager

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